Whole30 / Paleo Mississippi Pot Roast
This Whole30 / Paleo Mississippi Pot Roast is a delightful twist on a classic dish that brings comfort food to the table with clean, wholesome ingredients. Perfect for family dinners, special occasions, or meal prep, this pot roast is not only flavorful but also compliant with Whole30 and Paleo dietary guidelines. The combination of tender beef and zesty pepperoncini creates a dish that’s both satisfying and simple to prepare.
Why You’ll Love This Recipe
- Healthy Ingredients: This recipe uses clean ingredients that fit your Whole30 and Paleo lifestyle.
- Effortless Preparation: With minimal hands-on time and a slow cooker, you can have a delicious meal ready without much fuss.
- Flavorful and Tender: The unique flavor of pepperoncini combined with spices makes every bite deliciously tender.
- Versatile Serving Options: Enjoy it over mashed potatoes, rice, or on its own for a hearty meal.
- Great for Meal Prep: Make a large batch to enjoy during the week; it tastes even better the next day!
Tools and Preparation
To prepare this scrumptious Whole30 / Paleo Mississippi Pot Roast, you’ll need some essential kitchen tools. These will help streamline the cooking process and ensure great results.
Essential Tools and Equipment
- Slow cooker
- Large skillet
- Tongs
- Measuring cups and spoons
- Knife and cutting board
Importance of Each Tool
- Slow cooker: Allows for low-and-slow cooking, making the beef extra tender while you go about your day.
- Large skillet: Ideal for searing the chuck roast to lock in flavors before it goes into the slow cooker.
- Tongs: Great for handling hot meat without losing juices or making a mess.
- Measuring cups and spoons: Ensures accurate measurements for perfect seasoning every time.

Ingredients
This healthy take on a classic Mississippi Pot Roast combines clean ingredients to make this dish Paleo and Whole30 compliant.
For the Beef
- 3-5 lb beef chuck roast
For Searing
- 2 tbsp olive oil
For Flavoring
- 1 cup beef broth
- 1 tbsp dried chives
- 2 tsp garlic powder
- 2 tsp onion powder
- 1 tsp dried dill
- 1 tsp salt
- 1 tsp black pepper
For Peppers
- 6-8 pepperoncini peppers, whole
- 1-2 tbsp pepperoncini pepper juice (from the jar)
For Finishing Touches
- 4 tbsp ghee
How to Make Whole30 / Paleo Mississippi Pot Roast
Step 1: Prepare the Chuck Roast
- Take the chuck roast out of the fridge. Remove from packaging and pat dry with a paper towel.
- Generously season all sides with salt and pepper. Set aside.
Step 2: Sear the Beef
- Heat a couple of tablespoons of olive oil over medium-high to high heat in a large skillet until hot.
- Once the oil is shimmering, place the seasoned chuck roast in the skillet.
- Sear for about 1-2 minutes per side until deep golden brown.
- Transfer the chuck roast to the bowl of your slow cooker.
Step 3: Deglaze Your Skillet
- After removing the chuck roast, deglaze the pan over medium-high heat with 1 cup of beef broth.
- Bring to a boil while scraping up all the brown bits from the bottom of the pan.
- Continue cooking for 2-3 minutes until reduced by about half.
Step 4: Combine Ingredients in Slow Cooker
- Pour the liquid from your skillet over the chuck roast in your slow cooker.
- Sprinkle chives, garlic powder, onion powder, dill, salt, and pepper over everything.
- Arrange whole pepperoncini around the meat and add juice from their jar.
- Top with ghee or high-quality butter.
Step 5: Cook Your Pot Roast
- Cover with a lid and cook on low for 8-10 hours or on high for 5-6 hours.
- Check if it’s fork-tender; if not, cook an additional hour or two as needed.
Step 6: Serve It Up!
Serve your delicious Whole30 / Paleo Mississippi Pot Roast over mashed potatoes, polenta, rice, or simply enjoy it as is! Enjoy!
How to Serve Whole30 / Paleo Mississippi Pot Roast
Serving Whole30 / Paleo Mississippi Pot Roast can elevate your meal experience. This dish is versatile and pairs well with various sides that complement its rich flavors.
Over Mashed Cauliflower
- Mashed cauliflower is a creamy, low-carb alternative to traditional mashed potatoes, enhancing the savory taste of the pot roast.
With Rice
- Pairing your pot roast with rice offers a hearty base that soaks up the delicious juices, making for a satisfying meal.
On Its Own
- Enjoy the pot roast as is for a low-carb option. The tender beef and zesty peppers provide plenty of flavor without any sides.
With Polenta
- Creamy polenta adds a comforting texture and absorbs the flavorful broth, making it an excellent accompaniment to the roast.
As Tacos
- Shred the pot roast and use it as a filling for lettuce wraps or grain-free tortillas for a fun taco night twist.
Over Sweet Potato Mash
- Sweet potato mash brings natural sweetness, balancing the savory notes of the pot roast perfectly while keeping it Whole30 compliant.
How to Perfect Whole30 / Paleo Mississippi Pot Roast
To achieve an outstanding Whole30 / Paleo Mississippi Pot Roast, consider these helpful tips:
- Choose Quality Meat: Select a well-marbled beef chuck roast for better flavor and tenderness.
- Sear Properly: Don’t skip searing the meat; it locks in juices and adds depth to the flavor.
- Use Fresh Spices: Freshly dried herbs enhance flavor more than pre-ground spices. Consider using them for optimal taste.
- Adjust Cooking Time: If your meat isn’t fork-tender after cooking, allow additional time in the slow cooker until it reaches perfect tenderness.
- Let It Rest: Allow the pot roast to rest before slicing to keep it juicy. A few minutes will make a difference.
- Save Leftovers: Store leftovers in an airtight container in the fridge for easy meals throughout the week.
Best Side Dishes for Whole30 / Paleo Mississippi Pot Roast
Complete your meal with these fantastic side dishes that pair beautifully with Whole30 / Paleo Mississippi Pot Roast:
- Garlic Roasted Brussels Sprouts
These crispy sprouts add a delicious crunch and are packed with nutrients. - Zucchini Noodles
A light and refreshing option, zucchini noodles offer a low-carb alternative to pasta that complements the dish nicely. - Cauliflower Rice
A simple yet effective substitute for traditional rice, cauliflower rice is low in carbs and absorbs flavors well. - Roasted Asparagus
Tender roasted asparagus adds vibrant color and earthy flavor to your plate while being nutrient-dense. - Caramelized Carrots
Sweet and savory caramelized carrots bring out natural sugars that balance the richness of the pot roast. - Steamed Broccoli
Quick and easy steamed broccoli provides fiber and vitamins while adding a fresh element to your meal. - Cabbage Slaw
A crunchy slaw made from cabbage adds texture and brightness to each bite, perfect for contrasting with tender beef. - Spicy Cucumber Salad
This refreshing salad offers a crisp, tangy contrast that cuts through the richness of the pot roast, enhancing your dining experience.
Common Mistakes to Avoid
When preparing your Whole30 / Paleo Mississippi Pot Roast, avoiding common mistakes can help ensure a delicious outcome.
- Skipping the Searing: Failing to sear the beef before slow cooking can lead to a less flavorful dish. Always sear the roast to lock in juices and enhance flavor.
- Not Deglazing Properly: Neglecting to deglaze the pan can waste flavorful bits. Make sure to scrape up all the browned bits after searing for added depth in your pot roast.
- Overcrowding the Slow Cooker: Placing too much in your slow cooker can hinder proper cooking. Ensure there is enough space for even cooking; if necessary, cook in batches.
- Ignoring Cooking Times: Cooking for insufficient time can result in tough meat. Stick to the suggested cooking times and check tenderness before serving.
- Using Low-Quality Ingredients: Poor-quality beef or broth can affect taste. Opt for high-quality cuts of beef and fresh ingredients for the best results.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container.
- They will last for up to 3-4 days in the refrigerator.
Freezing Whole30 / Paleo Mississippi Pot Roast
- Allow the pot roast to cool before freezing.
- Store in freezer-safe containers or bags.
- It can be frozen for up to 2-3 months.
Reheating Whole30 / Paleo Mississippi Pot Roast
- Oven: Preheat to 350°F (175°C) and cover with foil. Heat until warmed through, about 20-30 minutes.
- Microwave: Use a microwave-safe container and heat on medium power, stirring occasionally until hot.
- Stovetop: Place in a skillet over low heat with a splash of broth or water. Stir occasionally until heated through.
Frequently Asked Questions
If you have questions regarding your Whole30 / Paleo Mississippi Pot Roast, you’re not alone! Here are some common inquiries:
Can I use a different cut of meat for this recipe?
Yes, you can substitute with other cuts like brisket or round roast. Just adjust cooking times as needed based on thickness.
How do I know when my pot roast is done?
The roast should be fork-tender when finished cooking. If it still feels tough, continue cooking for an additional hour or two.
Can I make this recipe in an Instant Pot?
Absolutely! Use the sauté function first, then pressure cook on high for about 60-70 minutes followed by natural release.
What should I serve with Whole30 / Paleo Mississippi Pot Roast?
This dish pairs well with mashed cauliflower, polenta, or simply enjoyed on its own for a hearty meal!
Final Thoughts
The Whole30 / Paleo Mississippi Pot Roast offers a delightful twist on a classic dish while adhering to clean eating principles. Its tender meat and rich flavors make it perfect for family dinners or meal prep. Feel free to customize with your favorite vegetables or side dishes!
Whole30 / Paleo Mississippi Pot Roast
Indulge in a comforting meal with this Whole30 / Paleo Mississippi Pot Roast, a wholesome take on a beloved classic. This recipe features tender beef chuck roast slow-cooked to perfection, infused with the zesty goodness of pepperoncini and an array of spices. The result is a rich, flavorful dish that’s not only compliant with clean eating standards but also incredibly easy to prepare. Ideal for family dinners or meal prep, this pot roast promises satisfaction in every bite. Serve it over mashed cauliflower or enjoy it on its own for a hearty, nourishing experience.
- Prep Time: 15 minutes
- Cook Time: 8 hours (low)
- Total Time: 8 hours 15 minutes
- Yield: Serves approximately 6 people 1x
- Category: Main
- Method: Slow Cooking
- Cuisine: American
Ingredients
- 3–5 lb beef chuck roast
- 2 tbsp olive oil
- 1 cup beef broth
- 6–8 whole pepperoncini peppers
- 4 tbsp ghee
- 1 tbsp dried chives
- 2 tsp garlic powder
- 2 tsp onion powder
- 1 tsp dried dill
- 1 tsp salt
- 1 tsp black pepper
- 1–2 tbsp pepperoncini pepper juice (from the jar)
Instructions
- Season the chuck roast with salt and pepper. Heat olive oil in a skillet and sear the roast for 1-2 minutes per side until golden brown. Transfer to a slow cooker.
- Deglaze the skillet with beef broth, scraping up browned bits. Pour over the roast in the slow cooker.
- Add spices and arrange pepperoncini around the meat. Top with ghee.
- Cover and cook on low for 8-10 hours or high for 5-6 hours until fork-tender.
Nutrition
- Serving Size: 1 serving
- Calories: 420
- Sugar: 1g
- Sodium: 680mg
- Fat: 28g
- Saturated Fat: 12g
- Unsaturated Fat: 16g
- Trans Fat: 0g
- Carbohydrates: 5g
- Fiber: 0g
- Protein: 36g
- Cholesterol: 130mg